Wasserstein distance-based probabilistic linguistic TODIM method with application to the evaluation of sustainable rural tourism potential

The evaluation of sustainable rural tourism potential is a key work in sustainable rural tourism development. Due to the complexity of the rural tourism development situation and the limited cognition of people, most of the assessment problems for sustainable rural tourism potential are highly uncertain, which brings challenges to the characterisation and measurement of evaluation information. Besides, decision-makers (DMs) usually do not exhibit complete rationality in the practical evaluation process. To tackle such problems, this paper proposes a new behaviour multi-attribute group decision-making (MAGDM) method with probabilistic linguistic terms sets (PLTSs) by integrating Wasserstein distance measure into TODIM (an acronym in Portuguese of interactive and multicriteria decision making) method. Firstly, a new Wasserstein-based distance measure with PLTSs is defined, and some properties of the proposed distance are developed. Secondly, based on the correlation coefficient among attributes and standard deviation of each attribute, an attribute weight determination method (called PL-CRITIC method) is proposed. Subsequently, a Wasserstein distance-based probabilistic linguistic TODIM method is developed. Finally, the proposed method is applied to the evaluation of sustainable rural tourism potential, along with sensitivity and comparative analyses, as a means of illustrating the effectiveness and advantages of the new method

Missile fixed-structure m controller design based on constrained PSO algorithm

This paper provides a method of fixed-structure m controller design with a novel particle swarm optimization (PSO) technique. The structured synthesis problem based on optimization is formulated and solved by a kind of constrained PSO algorithm which is relatively simple and without any new parameters added in the objective function. The experimental results tested on a set of 12 benchmark functions show that the proposed algorithm can outperform others in most cases. What is more, an air-to-air missile longitudinal channel control structure based on the proposed algorithm is studied and the simulation results are compared with other algorithms. The final comparison results also show the superior performance improvement over other algorithms

Spatiotemporal Analysis of Drought Characteristics in Song-Liao River Basin in China

The monthly accumulated precipitation and monthly average temperature of 117 meteorological stations in Song-Liao River Basin (SLRB) were used to calculate the Standardized Precipitation Evapotranspiration Indices (SPEI) to analyze the drought characteristics, including long-term trends, drought affected area, climate abrupt change, intensive drought occurrence regions, and drought durations during 1964–2013 with the support of GIS. The Area Drought Severity (ADS), a comprehensive index, is proposed to assess both the variations of drought degree and the extent of the drought affected area. The results revealed that (1) the drought happening probability and degree are rising and the affected areas of all degrees of drought have an increasing trend during the last 50 years; (2) there is a climate abrupt change which occurred in around 1994, and the area with declining SPEI is larger than that with declining SPI, which could be due to the rising temperature after the climate abrupt change; (3) all degrees of drought occurrence probability increased, and the intensive drought occurrence regions altered from the northern SLRB to the southwestern SLRB after the climate abrupt change; (4) the drought duration increased from 1994, and the increased drought durations occurred in most parts of SLRB

IRE1α promotes cell apoptosis and an inflammatory response in endoplasmic reticulum stress-induced rheumatoid arthritis fibroblast-like synovial cells by enhancing autophagy

Endoplasmic reticulum (ER) stress can induce autophagy via the unfolded protein response (UPR), and autophagy can regulate the activation of inflammasomes. Inositol-requiring enzyme 1α (IRE1α) is a transducer of the UPR in cells with ER stress. Here, we investigated the role of IRE1α and its impact on ER stress in rheumatoid arthritis fibroblast-like synovial cells (RA-FLSs). RA-FLSs were isolated from rheumatoid arthritis (RA) patients and stimulated with thapsigargin (TG) to produce ER stress cells. ER stress-, autophagy and the expression of apoptosis-associated factors were investigated by western blotting and the qRT-PCR. Cellular ROS levels were assessed by flow cytometry. ELISAs were performed to determine the concentrations of inflammatory mediators. TG treatment promoted IRE1α, GRP78, CHOP, and ATP6 mRNA and protein expression. ROS generation was increased in TG-induced RA-FLSs; additionally, TG was found to induce cell inflammation by upregulating the expression of inflammasome markers and the concentrations of inflammatory mediators. The levels of autophagy markers, apoptosis-associated proteins, and mRNA were increased in TG-stimulated RA-FLSs. However, transfection with si-IRE1α suppressed TG-induced increases in ROS generation, inflammation levels, cell apoptosis, and autophagy in RA-FLSs. Treatment with the autophagy activator RAPA attenuated the protective effects of IRE1α silencing on TG-induced RA-FLS apoptosis and inflammatory damage. Our findings showed that in RA-FLSs, IRE1α silencing alleviated ER stress-induced inflammation and apoptosis caused by autophagy

Investigation of Cerium-Lithium Sealing Treatment of Cobalt-based Conversion Coatings Formed on Aluminum Alloys

A study was conducted to examine methods of adjusting cerium-lithium sealing process parameters in order to improve the corrosion protection capabilities of a cobalt-based chemical conversion film. In order to seal the pores of the cobalt-based conversion coatings, samples were treated in a cerium-lithium deposition bath in optimal process conditions. The optimal treatment condition was determined by examination of finished samples using the scanning electron microscope (SEM) and electrochemical test measurements. The corrosion behaviors of the sealing coatings were studied using an open circuit potential-time monitoring technique (OCPT), electrochemical impedance spectroscopy (EIS), and potentiodynamic polarization tests in 3.5 wt.% NaCl solution. It was found that the best treatment process for the cobalt-based conversion coating was sealed in the cerium-lithium sealing solution for 2 h at 90 ℃. DOI: http://dx.doi.org/10.5755/j01.ms.24.4.19132</p

Effects of Nanoparticle Size and Radiation Energy on Copper-Cysteamine Nanoparticles for X-ray Induced Photodynamic Therapy

The Copper-cysteamine (Cu-Cy) nanoparticle is a novel sensitizer with a potential to increase the effectiveness of radiation therapy for cancer treatment. In this work, the effect of nanoparticle size and the energy of X-rays on the effectiveness of radiation therapy are investigated. The effect of the particle size on their performance is very complicated. The nanoparticles with an average size of 300 nm have the most intense photoluminescence, the nanoparticles with the average size of 100 nm have the most reactive oxygen species production upon X-ray irradiation, while the nanoparticles with the average size of 40 nm have the best outcome in the tumor suppression in mice upon X-ray irradiation. For energy, 90 kVp radiation resulted in smaller tumor sizes than 250 kVp or 350 kVp radiation energies. Overall, knowledge of the effect of nanoparticle size and radiation energy on radiation therapy outcomes could be useful for future applications of Cu-Cy nanoparticles